Kidney Transplant

Kidney Transplant

A Kidney Transplant is a surgical procedure in which a healthy kidney from a donor is placed into a person whose kidneys no longer function properly (end-stage renal disease). It is considered the best treatment for many patients with advanced kidney failure compared to long-term dialysis.

1. Definition

  • Replacement of a failed kidney with a healthy donor kidney.
  • The new kidney is usually placed in the lower abdomen (iliac fossa) and connected to the recipient’s blood vessels and bladder.
  • The diseased kidneys are usually not removed, unless there’s infection, cancer, or very large polycystic kidneys.

2. Indications

End-stage renal disease (ESRD) due to:

  • Diabetes mellitus (most common cause)
  • Hypertension
  • Chronic glomerulonephritis
  • Polycystic kidney disease
  • Congenital kidney problems

3. Donor Types

Living donor
  • Related (family member)
  • Unrelated (spouse, friend)
Deceased donor
  • From a person who has died (brain-dead or cardiac-death donor)

4. Advantages over Dialysis

  • Better quality of life
  • Longer survival
  • Freedom from dialysis
  • Fewer dietary restrictions

5. Post-Transplant Care

  • Lifelong immunosuppressive drugs (to prevent rejection) – e.g., tacrolimus, cyclosporine, mycophenolate, steroids
  • Regular monitoring of kidney function (blood tests, urine tests)
  • Infection prevention and healthy lifestyle

A kidney transplant is the best treatment for patients with end-stage kidney failure. It improves survival and quality of life compared to dialysis but requires lifelong medicines and monitoring to prevent rejection.